Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908656 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL21987080 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL21987011 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL5500682 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL2673508 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL456777 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL2673510 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL19265661 | 0.72 | ALDH1A1 (0.36) | ALDH1A1LMNAUSP2ALOX12KMT2A | |
| SCHEMBL11284764 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL3999543 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002735-B1 | PROCESS FOR THE PREPARATION OF PIPERONYLIDENECROTON AMIDES | HAARMANN & REIMER GMBH (DE) | 1980-12-10 | — | — | EP | disclosed |
| EP-0002734-B1 | PROCESS FOR THE PREPARATION OF PIPERONYLIDENECROTON AMIDES | HAARMANN & REIMER GMBH (DE) | 1980-09-17 | — | — | EP | disclosed |
| US-4209446-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF ALKALI METAL HYDROXIDE AND DIPOLAR APROTIC DILUENT | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |
| US-4209445-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM HYDROXIDE OR CROWN ETHER METAL COMPLEX | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |
| EP-0002734-A2 | Process for the preparation of piperonylidenecroton amides | HAARMANN & REIMER GMBH (DE) | 1979-07-11 | — | — | EP | disclosed |