Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440845 | 0.99 | NPSR1 (0.46) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL10340127 | 0.84 | MAPT (0.44) | NPSR1MEN1KMT2ASMN1; SMN2ATG4B | |
| SCHEMBL11447415 | 0.83 | MEN1 (0.45) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL4084570 | 0.76 | MEN1 (0.51) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL11447330 | 0.74 | MEN1 (0.49) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL11440932 | 0.74 | ATG4B (0.51) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL30426521 | 0.72 | EHMT2 (0.44) | NPSR1SMN1; SMN2MAPTRAB9AAPAF1 | |
| SCHEMBL11435038 | 0.72 | ATG4B (0.49) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL11435578 | 0.68 | MEN1 (0.57) | NPSR1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL27858086 | 0.67 | NPSR1 (0.54) | NPSR1MEN1KMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204063-A | ANTITUMOR AGENTS | LABORATORIOS MADE, S.A. (ES) | 1980-05-20 | — | — | US | disclosed |