Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781396 | 0.82 | NPC1 (0.67) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL11430304 | 0.82 | MAPT (0.58) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL11429228 | 0.82 | MAPT (0.50) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL27370252 | 0.81 | NPC1 (0.61) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL6797863 | 0.79 | MAPT (0.78) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL13902148 | 0.79 | NPC1 (0.56) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL3251704 | 0.78 | ALDH1A1 (0.61) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL11429866 | 0.78 | ALDH1A1 (0.50) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL20603945 | 0.78 | MAPT (0.62) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL8649480 | 0.78 | NPC1 (0.60) | MAPTNPC1RAB9AMAPK1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013145-A2 | Substituted anilinopyridines, processes for their preparation and intermediates for use therein, compositions and herbicidal use thereof | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |