Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354033 | 0.97 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL11132210 | 0.97 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| Bromide SCHEMBL11347475 | 0.95 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4790582 | 0.95 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL10725989 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL14110575 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| Bromide SCHEMBL11351615 | 0.76 | MAPT (0.37) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL10730506 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL31359400 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL29075804 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197124-A | SILVER OR COPPER AND SULFUR, SELENIUM OR TELLURIUM0 | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |