Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500139 | 0.86 | P2RY14 (0.32) | MARS1KDM4EGAAALDH1A1APOBEC3A | |
| SCHEMBL3577067 | 0.82 | MARS1 (0.45) | MARS1AURKARPS6KB1KDM4EGAA | |
| SCHEMBL11455736 | 0.81 | KDM4E (0.34) | KDM4EGAAALDH1A1POLBAPOBEC3A | |
| SCHEMBL11394213 | 0.78 | SMN1; SMN2 (0.32) | KDM4EGAAL3MBTL1APOBEC3AAPOBEC3G | |
| SCHEMBL1739452 | 0.76 | MARS1 (0.41) | MARS1AURKARPS6KB1KDM4EGAA | |
| SCHEMBL1741116 | 0.76 | CNR1 (0.48) | MARS1AURKARPS6KB1KDM4EGAA | |
| SCHEMBL1739296 | 0.74 | MARS1 (0.45) | MARS1AURKARPS6KB1ALDH1A1POLB | |
| SCHEMBL11365648 | 0.74 | HCAR2 (0.49) | MARS1HCAR3PTGER1HCAR2 | |
| SCHEMBL3646146 | 0.73 | MARS1 (0.46) | MARS1AURKARPS6KB1KDM4EGAA | |
| SCHEMBL2360638 | 0.73 | AURKA (0.60) | MARS1AURKARPS6KB1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |