SCHEMBL11436271

SCHEMBL11436271

[NH]P([NH])(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318686 0.88
SCHEMBL88352 0.75
Phosphoric Acid SCHEMBL11132493 0.75
SCHEMBL28006791 0.75 CA2 (0.46)
SCHEMBL634685 0.75 CA2 (0.46)
SCHEMBL31402615 0.75 CA2 (0.46)
Phosphoric Acid SCHEMBL6118900 0.75
SCHEMBL122502 0.75
SCHEMBL2486859 0.75 CA2 (0.46)
Phosphoric Acid SCHEMBL27534908 0.75 CA2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101301294-A Combinated inhibitors of FBP-ase and antidiabetic agents for diabetes treatment METABEHJSIS TERAP JUTIKS INK (US) 2008-11-12 CN disclosed
CN-100396283-C Combination of FBP enzyme inhibitor and antidiabetic agent for treating diabetes METABASIS THERAPEUTICS INC (US) 2008-06-25 CN disclosed
CN-1599612-A Combination of FBP enzyme inhibitor and antidiabetic agent for treating diabetes METABASIS THERAPEUTICS INC (US) 2005-03-23 CN disclosed
EP-0014386-A3 PHOSPHORAMIDO(DI)THIOATE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PESTICIDAL COMPOSITIONS CONTAINING THEM, AS WELL AS INTERMEDIATES ROHM AND HAAS COMPANY (US) 1980-10-15 EP disclosed
EP-0014386-A2 Phosphoramido(di)thioate derivatives, processes for their preparation and pesticidal compositions containing them, as well as intermediates ROHM AND HAAS COMPANY (US) 1980-08-20 EP disclosed