Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.62 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.62 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.62 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524443 | 0.84 | PDK1 (0.68) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL3535796 | 0.84 | PDK1 (0.68) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL11806675 | 0.80 | PDK1 (0.59) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL29191887 | 0.79 | PDK1 (0.62) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL10386144 | 0.78 | PDK1 (0.60) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL28316139 | 0.78 | PDK1 (0.60) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL5735974 | 0.77 | PDK1 (1.00) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL27573746 | 0.77 | PDK1 (0.59) | PDK1PDK2PDK3PDK4L3MBTL1 | |
| SCHEMBL6348877 | 0.77 | PDK1 (1.00) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL5551534 | 0.77 | PDK1 (0.68) | PDK1PDK2PDK3PDK4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218477-A | LONG LASTING ORAL AGENTS | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1980-08-19 | — | — | US | claimed |