Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412672 | 0.93 | APEX1 (0.69) | APEX1RAB9ANPC1KDRKMT2A | |
| SCHEMBL11433857 | 0.92 | APEX1 (0.58) | APEX1RAB9ANPC1KDRKMT2A | |
| SCHEMBL11434114 | 0.90 | APEX1 (0.60) | APEX1RAB9ANPC1KDRKMT2A | |
| SCHEMBL10413406 | 0.85 | MEN1 (0.58) | APEX1RAB9ANPC1KDRKMT2A | |
| SCHEMBL13619183 | 0.84 | APEX1 (0.81) | APEX1RAB9ANPC1KDRKMT2A | |
| SCHEMBL11421997 | 0.84 | RAB9A (0.59) | RAB9ANPC1KDRKMT2AMEN1 | |
| SCHEMBL11423384 | 0.84 | RAB9A (0.62) | APEX1RAB9ANPC1KDRKMT2A | |
| SCHEMBL11433791 | 0.84 | SMN1; SMN2 (0.57) | APEX1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11424317 | 0.84 | MAPT (0.57) | APEX1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11766331 | 0.84 | RAB9A (0.55) | APEX1RAB9ANPC1KDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |