Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305666 | 0.87 | ESRRG (0.50) | DRD2ESRRGSLC18A3SIGMAR1 | |
| SCHEMBL12670254 | 0.86 | CYP2C9 (0.60) | DRD2ESRRGSIGMAR1CYP2C9 | |
| Hydrochloric Acid SCHEMBL5353922 | 0.86 | ESRRG (0.52) | DRD2ESRRGSLC18A3SIGMAR1 | |
| SCHEMBL11439538 | 0.84 | DRD2 (0.47) | DRD2ESRRGSLC18A3 | |
| SCHEMBL24724942 | 0.83 | ESRRG (0.45) | DRD2ESRRGSLC18A3SIGMAR1CYP2C9 | |
| SCHEMBL63749 | 0.83 | KDM4E (0.51) | ATMDRD2ESRRG | |
| SCHEMBL2743285 | 0.81 | HDAC3 (0.55) | — | |
| SCHEMBL3222423 | 0.80 | HDAC8 (0.50) | CYP2C9 | |
| SCHEMBL13041545 | 0.80 | SLC18A3 (0.61) | ATMDRD2SLC18A3 | |
| SCHEMBL19089526 | 0.80 | HDAC1 (0.44) | DRD2SLC18A3SIGMAR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188396-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |