Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTGIR | P43119 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330151 | 0.87 | MCHR1 (0.47) | KCNH2TP53MCHR1PTGIRREN | |
| Clanobutin SCHEMBL5055263 | 0.87 | PTGIR (0.56) | TP53PTGIRLMNATSHR | |
| Clanobutin SCHEMBL667903 | 0.87 | PTGIR (0.56) | TP53PTGIRLMNATSHR | |
| Clanobutin SCHEMBL3850118 | 0.86 | PTGIR (0.55) | TP53PTGIRLMNATSHR | |
| SCHEMBL11946690 | 0.83 | PTGIR (0.55) | TP53PTGIRLMNATSHR | |
| SCHEMBL11314317 | 0.83 | PTGIR (0.52) | TP53PTGIRLMNATSHR | |
| SCHEMBL11115783 | 0.82 | PTGIR (0.54) | TP53PTGIRLMNATSHR | |
| SCHEMBL11116578 | 0.82 | PTGIR (0.54) | TP53PTGIRLMNATSHR | |
| SCHEMBL11117499 | 0.82 | PTGIR (0.54) | TP53PTGIRLMNATSHR | |
| SCHEMBL29851413 | 0.82 | POLB (0.45) | TP53MAPTTHRBPOLBPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205088-A | GASTROINTESTINAL DISORDERS, CARDIOVASCULAR DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-05-27 | — | — | US | claimed |
| US-4034111-A | INTESTINAL SECRETION AND CARDIAC STIMULATION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-07-05 | — | — | US | claimed |
| US-4205088-A | GASTROINTESTINAL DISORDERS, CARDIOVASCULAR DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-05-27 | — | — | US | disclosed |
| US-4034111-A | INTESTINAL SECRETION AND CARDIAC STIMULATION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-07-05 | — | — | US | disclosed |