⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20543786 | 0.78 | — | — | |
| SCHEMBL18576104 | 0.75 | — | — | |
| SCHEMBL11836936 | 0.72 | MEN1 (0.71) | — | |
| SCHEMBL23082007 | 0.69 | — | — | |
| SCHEMBL14685169 | 0.69 | — | — | |
| Methoxymethane SCHEMBL27743090 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL8735137 | 0.69 | MEN1 (0.43) | — | |
| SCHEMBL27528739 | 0.67 | MEN1 (0.48) | — | |
| SCHEMBL27823397 | 0.67 | MEN1 (0.41) | — | |
| SCHEMBL11841959 | 0.65 | MEN1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216163-A1 | 1,2,2,2-TETRAFLUOROETHYL METHYL ETHER PRODUCTION METHOD | セントラル硝子株式会社 (JP) | 2019-11-14 | — | — | WO | disclosed |
| US-9388208-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| EP-0005810-B1 | METHOD FOR THE PREPARATION OF ORGANIC FLUORO COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-12 | — | — | EP | disclosed |
| EP-0005810-A1 | Method for the preparation of organic fluoro compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-12-12 | — | — | EP | disclosed |
| US-3980714-A | INHALATION ANESTHETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |