Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143870 | 0.84 | GSK3B (0.61) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL13464654 | 0.83 | ALDH2 (0.49) | ALDH2MAOAMAOBMAPTMEN1 | |
| SCHEMBL12292945 | 0.81 | MEN1 (0.43) | MAPTMEN1KMT2ASMN1; SMN2GSK3B | |
| SCHEMBL19781538 | 0.81 | ALDH2 (0.49) | ALDH2MAOAMAOBMAPTMEN1 | |
| SCHEMBL3411823 | 0.77 | SMN1; SMN2 (0.44) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11428068 | 0.76 | NPC1 (0.52) | MAPTMEN1KMT2ASMN1; SMN2GSK3B | |
| SCHEMBL10762254 | 0.73 | MAOB (0.47) | MAOBMEN1KMT2AGSK3BPOLB | |
| SCHEMBL27901075 | 0.72 | NQO1 (0.45) | MAOBMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29893480 | 0.72 | FFAR4 (0.56) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11422111 | 0.71 | POLB (0.44) | ALDH2MAOAMAOBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399509-B2 | Glucopyranoside derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399509-B2 | Glucopyranoside derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-8399509-B2 | Glucopyranoside derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| EP-2260051-B1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | disclosed |
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-02-03 | — | — | US | disclosed |
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-02-03 | — | — | US | disclosed |
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-02-03 | — | — | US | disclosed |
| EP-2260051-A1 | GLUCOPYRANOSIDE DERIVATIVES | Merck Patent GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009124638-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | UGGT1, SLC5A1, SLC5A2 | ALDH2 1320/4885MAOA 4171/4885MAOB 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.