Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010863 | 0.85 | TAAR1 (0.60) | NPC1SMN1; SMN2MAOBTAAR1 | |
| SCHEMBL7773473 | 0.84 | GAA (0.72) | GAALMNAMAPK1PPARAESR1 | |
| SCHEMBL11554967 | 0.84 | GAA (0.72) | HPGDGAAKDM4EALDH1A1LMNA | |
| SCHEMBL9482870 | 0.84 | HPGD (0.58) | HPGDGAAKDM4EALDH1A1LMNA | |
| SCHEMBL20806916 | 0.84 | CYP19A1 (0.66) | HPGDGAALMNAHTTESR1 | |
| Hydrochloric Acid SCHEMBL1290885 | 0.83 | TAAR1 (0.58) | ALDH1A1LMNASMN1; SMN2MAOBTAAR1 | |
| SCHEMBL13299419 | 0.83 | GAA (0.60) | HPGDGAAKDM4EALDH1A1LMNA | |
| SCHEMBL21567534 | 0.83 | NPC1 (0.62) | HPGDGAAALDH1A1LMNANPC1 | |
| SCHEMBL11439341 | 0.83 | NPC1 (0.55) | GAAALDH1A1LMNANPC1SRD5A2 | |
| SCHEMBL21991829 | 0.81 | PPARA (0.62) | HPGDGAAKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215139-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1980-07-29 | — | — | US | disclosed |