Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MGAM | O43451 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | SI | P14410 | 4/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | QPCT | Q16769 | 2/20 | 0.57 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903833 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL6663651 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL23292523 | 0.81 | KDM4E (0.69) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL9342320 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL17713905 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL20522413 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL6154686 | 0.80 | NOTUM (0.71) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL6539262 | 0.80 | KDM4E (0.97) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL13912997 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1MAPTHSD17B10TP53 | |
| SCHEMBL22761303 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1MAPTHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250364276-A1 | TUNABLE LOW-COST PASSIVATION COATING FOR FACILITATING FLUXLESS BONDING OF COPPER SOLDER INTERCONNECTS IN FLIP CHIP ASSEMBLY | UNIV NORTH TEXAS (US) | 2025-11-27 | — | — | US | claimed |
| CN-119563048-A | Passivation coating on copper metal surfaces for copper wire bonding applications | 北德克萨斯大学 | 2025-03-04 | — | — | CN | claimed |
| US-20210071308-A1 | SELECTIVE SURFACE FINISHING FOR CORROSION INHIBITION VIA CHEMICAL VAPOR DEPOSITION | UNIVERSITY OF NORTH TEXAS | 2021-03-11 | — | — | US | claimed |
| CN-108299964-A | Anti-aging coating of insulation for outdoor box switchyard and preparation method thereof | 河南龙翔电气股份有限公司 | 2018-07-20 | — | — | CN | claimed |
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | claimed |
| CN-106340344-B | Non-aging insulation cable and preparation method thereof | 河南开启电力实业有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-106373641-A | Double-capacity electric cable and manufacture method therefor | 河南开启电力实业有限公司 | 2017-02-01 | — | — | CN | claimed |
| CN-106340344-A | Aging-resistant insulated cable and preparation method thereof | 河南开启电力实业有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-106187945-A | A kind of synthetic method of organic synthesis intermediate | 辽宁师范大学 | 2016-12-07 | — | — | CN | claimed |
| CN-105694192-A | High heat resistant and radiation resistant cable sheath material | 临海市亚东特种电缆料厂 | 2016-06-22 | — | — | CN | claimed |
| CN-102875887-B | Low-smoke halogen-free flame-retardant electric insulation material for cables | LINHAI CITY YADONG SPECIAL CABLE MATERIAL FACTORY | 2015-01-28 | — | — | CN | claimed |
| US-8470820-B2 | Nitrogen-containing heteroaryl derivatives | HOFFMAN-LA ROCHE INC. (US) | 2013-06-25 | — | — | US | claimed |
| EP-1658072-A4 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PROD INC (US) | 2009-03-25 | — | — | EP | claimed |
| US-20070270426-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER INC. | 2007-11-22 | — | — | US | claimed |
| US-7253195-B2 | Compounds for the treatment of neurodegenerative disorders | PFIZER INC (US) | 2007-08-07 | — | — | US | claimed |
| EP-1658072-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2006-05-24 | — | — | EP | claimed |
| WO-2005020991-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS, INC. (US) | 2005-03-10 | — | — | WO | claimed |
| US-20050043372-A1 | Compounds for the treatment of neurodegenerative disorders | PFIZER, INC. (US) | 2005-02-24 | — | — | US | claimed |
| CN-122095010-A | Silicone-based optically clear adhesives with corrosion resistance | — | 2026-05-26 | — | — | CN | disclosed |
| EP-0005783-A1 | Imidazo (2.1-b)-(1.3.4)-thiadiazoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270426-A1 | COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | APP, BACE1, PSEN1 | KDM4E 3582/4885ALDH1A1 2945/4885MAPT 9/4885 |
| US-20050043372-A1 | Compounds for the treatment of neurodegenerative disorders | APP, BACE1, PSEN1 | KDM4E 3582/4885ALDH1A1 2945/4885MAPT 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.