Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.97 |
| ▸ | RAB9A | P51151 | 7/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.97 |
| ▸ | NPC1 | O15118 | 5/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.97 |
| ▸ | TP53 | P04637 | 2/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | MGAM | O43451 | 4/20 | 0.64 |
| ▸ | SI | P14410 | 4/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323592 | 0.86 | RAB9A (1.00) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL6538920 | 0.83 | RAB9A (0.94) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL17713905 | 0.81 | KDM4E (0.76) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL20703807 | 0.80 | NOTUM (1.00) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL1143740 | 0.80 | KDM4E (1.00) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL16479583 | 0.79 | RAB9A (0.78) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL3107207 | 0.79 | RAB9A (0.76) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL1868793 | 0.78 | KDM4E (0.66) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL27903833 | 0.78 | KDM4E (0.96) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL21156447 | 0.78 | RAB9A (0.74) | KDM4ERAB9ASMN1; SMN2NPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743776-B2 | ANTIFUNGAL, BETA-1,3-GLUCAN SYNTHASE INHIBITOR, PNEUMOCYSTIS CARINII; AMIDATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| US-20020193560-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2002-12-19 | — | — | US | disclosed |
| EP-0941236-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998023637-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193560-A1 | CYCLOHEXAPEPTIDES HAVING ANTIMICROBIAL ACTIVITY | NGLY1, CHIT1, MANBA | KDM4E 4695/4885RAB9A 3674/4885SMN1; SMN2 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.