Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437641 | 1.00 | CYP2D6 (0.50) | CYP2D6HIF1ACYP1A2APEX1BHMT | |
| SCHEMBL17347852 | 1.00 | CYP2D6 (0.50) | CYP2D6HIF1ACYP1A2APEX1BHMT | |
| SCHEMBL7845774 | 0.85 | GABRR1 (0.46) | CYP1A2APEX1GABRR1BLMTP53 | |
| SCHEMBL12387154 | 0.84 | CYP2D6 (0.48) | CYP2D6HIF1ACYP1A2BHMTBLM | |
| SCHEMBL16790758 | 0.84 | APEX1 (0.39) | CYP1A2APEX1GABRR1BLMTP53 | |
| SCHEMBL12989556 | 0.82 | CYP2D6 (0.46) | CYP2D6HIF1ACYP1A2BHMTGABRR1 | |
| SCHEMBL2203031 | 0.80 | — | — | |
| SCHEMBL17530133 | 0.80 | GABRR1 (0.42) | CYP1A2APEX1BHMTGABRR1BLM | |
| SCHEMBL16549367 | 0.79 | CYP2D6 (0.42) | CYP2D6HIF1ABLMTP53GMNN | |
| SCHEMBL17640332 | 0.79 | CYP2D6 (0.42) | CYP2D6HIF1ABLMTP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233414-A | FOR SYNTHETIC RESINS HEAT RESISTANCE | ARGUS CHEMICAL CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4174297-A | Polyhydric phenol coester stabilizers | ARGUS CHEMICAL CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |