Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429769 | 1.00 | PGR (0.62) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11433111 | 0.98 | PGR (0.58) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11442001 | 0.96 | PGR (0.61) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11423938 | 0.96 | PGR (0.61) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11422372 | 0.96 | PGR (0.66) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11431381 | 0.96 | PGR (0.56) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11433534 | 0.96 | PGR (0.56) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11424195 | 0.95 | PGR (0.60) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11431503 | 0.94 | PGR (0.55) | PGRCYP3A4NR3C1HIF1ALMNA | |
| SCHEMBL11433544 | 0.94 | PGR (0.55) | PGRCYP3A4NR3C1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |