Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.67 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437613 | 0.87 | CYP19A1 (0.51) | CYP19A1CCR6KCNH2NPY2RCETP | |
| SCHEMBL11445508 | 0.85 | CYP19A1 (0.67) | CYP19A1CCR6KCNH2NPY2RNR1H2 | |
| Bromide SCHEMBL11731087 | 0.82 | CYP19A1 (0.46) | CYP19A1CCR6KCNH2NPY2RCETP | |
| SCHEMBL7713437 | 0.82 | CYP19A1 (0.67) | CYP19A1CCR6KCNH2NPY2RABL1 | |
| SCHEMBL11433294 | 0.81 | CYP19A1 (0.45) | CYP19A1CCR6KCNH2NPY2RTRPV1 | |
| SCHEMBL9720397 | 0.77 | CYP19A1 (0.73) | CYP19A1CCR6KCNH2NPY2REPHX2 | |
| SCHEMBL11725562 | 0.76 | CYP19A1 (0.54) | CYP19A1CCR6KCNH2NPY2REPHX1 | |
| SCHEMBL122607 | 0.73 | CYP19A1 (0.86) | CYP19A1NPY2R | |
| SCHEMBL10900702 | 0.73 | TRPV1 (0.41) | CYP19A1TRPV1ABL1 | |
| SCHEMBL11445510 | 0.73 | CYP19A1 (0.64) | CYP19A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |