Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726054 | 0.88 | CYP3A4 (0.60) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11445511 | 0.86 | CYP19A1 (0.67) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL913343 | 0.78 | CYP19A1 (0.79) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10900702 | 0.78 | TRPV1 (0.41) | CYP19A1CYP3A4CYP3A5TRPV1 | |
| SCHEMBL11439269 | 0.77 | CYP3A4 (0.51) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10631898 | 0.76 | CYP19A1 (0.86) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11439074 | 0.73 | CYP19A1 (0.67) | CYP19A1TRPV1 | |
| SCHEMBL27282169 | 0.72 | CYP19A1 (0.86) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11433292 | 0.71 | TRPV1 (0.36) | CYP19A1CYP3A4CYP3A5TRPV1 | |
| SCHEMBL194052 | 0.71 | TSHR (0.44) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |