Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428824 | 0.89 | KCNA3 (0.41) | KCNA3BRD9KDM4ETGFBR1SLC11A2 | |
| SCHEMBL11433951 | 0.87 | BRD9 (0.46) | KCNA3BRD9KDM4ETGFBR1PARP10 | |
| SCHEMBL11442564 | 0.86 | KDM4E (0.42) | BRD9KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL11547968 | 0.86 | BRD9 (0.42) | KCNA3BRD9KDM4EMEN1ALDH1A1 | |
| SCHEMBL31295875 | 0.86 | BRD9 (0.42) | KCNA3BRD9KDM4EMEN1ALDH1A1 | |
| SCHEMBL11434477 | 0.85 | MAPT (0.45) | KCNA3BRD9KDM4ECYP1A2CYP2C19 | |
| SCHEMBL11435071 | 0.85 | BRD9 (0.44) | BRD9KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL11426704 | 0.84 | BRD9 (0.43) | BRD9KDM4ETGFBR1PARP10PARP11 | |
| SCHEMBL11425957 | 0.84 | KCNA3 (0.43) | KCNA3BRD9KDM4ETGFBR1MAPK14 | |
| SCHEMBL11428480 | 0.84 | MAOB (0.41) | BRD9KDM4EMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |