SCHEMBL11440261

SCHEMBL11440261

Cc1cc(NC(=O)C2(C)CC2)ccc1S(N)(=O)=O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
ALDH1A1 P00352 2/20 0.48
PTGES2 Q9H7Z7 1/20 0.44
CA2 P00918 6/20 0.43
CA1 P00915 4/20 0.43
CA12 O43570 3/20 0.43
CA9 Q16790 3/20 0.43
CA7 P43166 2/20 0.42
BACE1 P56817 1/20 0.41
THRB P10828 1/20 0.40
GAA P10253 2/20 0.40
CYP26A1 O43174 3/20 0.39
PDIA6 Q15084 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11433255 0.87 ALDH1A1 (0.64) CNR1CNR2ALDH1A1BACE1THRB
SCHEMBL11427426 0.85 CNR1 (0.45) CNR1CNR2CA2CA1CA12
SCHEMBL11434797 0.85 CNR1 (0.47) CNR1CNR2ALDH1A1BACE1THRB
SCHEMBL11426827 0.84 CNR1 (0.47) CNR1CNR2ALDH1A1BACE1THRB
SCHEMBL11427182 0.84 CNR1 (0.42) CNR1CNR2CA2CA1CA12
SCHEMBL6192129 0.79 ALDH1A1 (0.73) ALDH1A1PTGES2CA2CA1CA12
SCHEMBL15886280 0.77 BACE1 (0.52) CNR1CNR2BACE1MEN1KMT2A
SCHEMBL11565472 0.75 CNR1 (0.43) CNR1CNR2BACE1GAAMEN1
SCHEMBL29740181 0.75 ALDH1A1 (0.50) ALDH1A1PTGES2CA2CA1CA12
SCHEMBL11427970 0.74 NPC1 (0.48) CNR1CNR2ALDH1A1BACE1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4184867-A Cycloalkanecarboxanilide derivative herbicides SHELL OIL COMPANY (US) 1980-01-22 US disclosed