Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | MATK | P42679 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426339 | 0.96 | AURKB (0.52) | AURKBAURKAPRKD3NR4A1CDC7 | |
| SCHEMBL11441473 | 0.93 | AURKA (0.50) | AURKBAURKANR4A1KCNMA1HSD17B10 | |
| SCHEMBL11440861 | 0.92 | AURKB (0.52) | AURKBAURKAPRKD3NR4A1CDC7 | |
| SCHEMBL11426487 | 0.88 | AURKA (0.44) | AURKBAURKAKCNMA1HSD17B10RAB9A | |
| SCHEMBL11427880 | 0.87 | AURKB (0.49) | AURKBAURKAPRKD3NR4A1CDC7 | |
| SCHEMBL11433621 | 0.87 | SNCA (0.45) | AURKBAURKAPRKD3KCNMA1HSD17B10 | |
| SCHEMBL11427850 | 0.87 | AURKA (0.43) | AURKBAURKAPRKD3KCNMA1HSD17B10 | |
| SCHEMBL11423958 | 0.86 | KCNMA1 (0.53) | AURKBAURKAPRKD3CDC7EEF2K | |
| SCHEMBL11425033 | 0.84 | AURKB (0.47) | AURKBAURKAPRKD3NR4A1CDC7 | |
| SCHEMBL11438690 | 0.84 | TTR (0.43) | AURKBAURKAKCNMA1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |