⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198860 | 1.00 | — | — | |
| SCHEMBL289020 | 0.79 | — | — | |
| SCHEMBL21722698 | 0.78 | — | — | |
| SCHEMBL5907143 | 0.77 | — | — | |
| SCHEMBL7489938 | 0.72 | — | — | |
| SCHEMBL9108322 | 0.69 | — | — | |
| SCHEMBL191998 | 0.69 | — | — | |
| SCHEMBL285299 | 0.69 | — | — | |
| SCHEMBL36515 | 0.69 | — | — | |
| SCHEMBL13889160 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957242-A | A kind of schiff base compounds and preparation method thereof and pharmaceutical applications | 四川省人民医院 | 2017-07-18 | — | — | CN | claimed |
| EP-3512852-B1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-20220390458-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-12-08 | — | — | US | disclosed |
| CN-109715631-B | TRAF6 inhibitors | 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） | 2022-02-18 | — | — | CN | disclosed |
| US-11185548-B2 | Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases | HELMHOLTZ ZENTRUM MUNCHEN—DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-11-30 | — | — | US | disclosed |
| US-11001591-B2 | TRAF 6 inhibitors | HELMHOLTZ ZENTRUM MUENCHEN—DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-05-11 | — | — | US | disclosed |
| WO-2021058490-A2 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-04-01 | — | — | WO | disclosed |
| EP-3795643-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | Centre National de la Recherche Scientifique (FR) | 2021-03-24 | — | — | EP | disclosed |
| US-20210017183-A1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH) (DE) | 2021-01-21 | — | — | US | disclosed |
| US-20200277297-A1 | TRAF 6 INHIBITORS | HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2020-09-03 | — | — | US | disclosed |
| US-20040038999-A1 | 6-alkoxy-pyrido-pyrimidines | ROCHE PALO ALTO LLC | 2004-02-26 | — | — | US | disclosed |
| WO-2004014907-A1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-19 | — | — | WO | disclosed |
| US-6586106-B2 | Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces | YUPO CORPORATION (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20020054991-A1 | Thermoplastic resin film satisfactory in printability | YUPO CORPORATION (JP) | 2002-05-09 | — | — | US | disclosed |
| EP-1172400-A1 | THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY | Yupo Corporation (JP) | 2002-01-16 | — | — | EP | disclosed |
| CN-1109749-A | Methods for inhibiting uterine fibrosis | LILLY CO ELI (US) | 1995-10-11 | — | — | CN | disclosed |
| CN-1105853-A | Methods for inhibiting bone loss | LILLY CO ELI (US) | 1995-08-02 | — | — | CN | disclosed |
| CN-1105362-A | Methods for lowering serum cholesterol | LILLY CO ELI (US) | 1995-07-19 | — | — | CN | disclosed |
| US-4180655-A | ANTITUMOR AND ANTILEUKEMIA AGENTS | Suami, Tetsuo (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4086415-A | ANTILEUKEMIA, ANTITUMOR | Suami, Tetsuo (JA) | 1978-04-25 | — | — | US | disclosed |