Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11317728 | 0.86 | CYP3A4 (0.33) | CA1CA2ALDH1A1THRBMAPK1 | |
| SCHEMBL11306569 | 0.82 | GAA (0.31) | PTGS1PTGS2GAAKMT2A | |
| SCHEMBL11785540 | 0.80 | KDM4E (0.38) | PTGS2CA1CA2TXNRD1KDM4E | |
| SCHEMBL11322932 | 0.78 | CYP3A4 (0.38) | MEN1ALDH1A1THRBMAPK1RECQL | |
| SCHEMBL10788045 | 0.77 | NPC1 (0.33) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL15020315 | 0.73 | GSK3B (0.37) | PTGS1PTGS2FAAHCA1CA2 | |
| SCHEMBL15020313 | 0.73 | GSK3B (0.37) | PTGS1PTGS2FAAHCA1CA2 | |
| SCHEMBL17253275 | 0.73 | GSK3B (0.37) | PTGS1PTGS2FAAHCA1CA2 | |
| SCHEMBL11305866 | 0.72 | PABPC1 (0.49) | CA2KDM4EMEN1NPC1USP2 | |
| SCHEMBL11406725 | 0.71 | HSP90AA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |