Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599130 | 0.84 | ATM (1.00) | ATMTP53NPY5RRAB9APOLB | |
| SCHEMBL14141312 | 0.81 | KCNH2 (0.53) | ATMTP53RAB9APOLBKMT2A | |
| SCHEMBL5725407 | 0.79 | ATM (0.69) | ATMTP53NPY5RRAB9APOLB | |
| SCHEMBL13543091 | 0.78 | ATM (0.49) | ATMTP53NPY5RRAB9APOLB | |
| Hydrochloric Acid SCHEMBL7667104 | 0.78 | SLC6A4 (0.54) | ATMTP53POLBDCUN1D1CCR5 | |
| SCHEMBL2959297 | 0.77 | DCUN1D1 (0.75) | DCUN1D1 | |
| SCHEMBL3809371 | 0.76 | SLC6A4 (0.51) | CCR5SLC6A2SLC6A4KCNH2 | |
| SCHEMBL14336844 | 0.75 | NPY5R (0.69) | ATMNPY5RCCR5 | |
| SCHEMBL14337147 | 0.75 | NPY5R (0.69) | ATMNPY5RCCR5 | |
| SCHEMBL15273035 | 0.73 | POLB (0.55) | ATMTP53POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013878-A1 | 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1980-08-06 | — | — | EP | disclosed |