Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442548 | 1.00 | ALDH1A1 (0.38) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11441403 | 0.89 | SMN1; SMN2 (0.37) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11436718 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11450498 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11450496 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11435695 | 0.82 | CHRM3 (0.39) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11438333 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11465725 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11446840 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 | |
| SCHEMBL11447829 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMITFSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | claimed |
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |