SCHEMBL11442003

SCHEMBL11442003

C=CC(=O)OC(CCC)[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.39
HPGD P15428 1/20 0.39
THRB P10828 3/20 0.33
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477448 0.88 TSHR (0.43) TSHRHPGDTHRB
SCHEMBL15477580 0.88 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL23581898 0.87 TSHR (0.42) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL15477784 0.87 TSHR (0.42) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL1931611 0.85 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL9637778 0.84 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL3905874 0.81 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1680181 0.79 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28289488 0.79 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL16538072 0.79 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140050917-A1 LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES NANOFILM LTD. (US) 2014-02-20 US claimed
US-12371447-B2 Method for producing (meth)acryloxy group-containing organosilicon compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-07-29 US disclosed
EP-4174076-B1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHINETSU CHEMICAL CO (JP) 2024-07-24 EP disclosed
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
EP-4174076-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-05-03 EP disclosed
US-20140050917-A1 LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES NANOFILM LTD. (US) 2014-02-20 US disclosed
US-4207373-A IMPACT STRENGTH ALLIED CHEMICAL CORPORATION (US) 1980-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371447-B2 Method for producing (meth)acryloxy group-containing organosilicon compounds HM13, RPS13, GRHPR TSHR 765/4885HPGD 334/4885THRB 2943/4885
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS HM13, RPS13, GRHPR TSHR 765/4885HPGD 334/4885THRB 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.