Sugi Predict

Sugi Predict / Targets / GRHPR

GRHPR

Glyoxylate reductase/hydroxypyruvate reductase · Q9UBQ7 · GRHPR on Sugi Atlas →

0 patent compounds predicted against GRHPR, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GRHPR by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons PHASE4COMPLETED
The Role of 5-alpha Reductase in Mediating Testosterone Actions PHASE4COMPLETED
Effect of Genetic Polymorphisms of UGT on the PKs of Indapamide in Egyptians PHASE4UNKNOWN
Renal Protective Effect of ACEI and ARB in Primary Hyperoxaluria PHASE3WITHDRAWN
Comparative Analysis Between Ringer's Lactate vs Plasma Lyte-A as Cardiopulmonary Bypass Prime PHASE3UNKNOWN
Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer PHASE3COMPLETED
Hydroxyproline Influence on Oxalate Metabolism PHASE1/PHASE2COMPLETED
Asymptomatic Carotid Artery Plaque Study (ACAPS) PHASE2COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis PHASE2UNKNOWN
Long-Term Study of Nitisinone to Treat Alkaptonuria PHASE2COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Iron Supplements Effect on b-Phe Levels in PKU Patients During 3 Years Study PHASE2COMPLETED
Serine Supplementation for Obese Subjects With Fatty Liver Disease PHASE1/PHASE2COMPLETED
An Individual Patient, Open Label Study to Use ACER-001 to Treat Combined D,L-2 Hydroxyglutaric Aciduria (C-2HGA) PHASE1ENROLLING_BY_INVITATION
Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers PHASE1COMPLETED
Tolerability of Enteral NAC in Infants PHASE1NOT_YET_RECRUITING
Rare Kidney Stone Consortium Biobank nanRECRUITING
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted Therapy nanUNKNOWN
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
Effect of Surgical or Conservative Approach in Patients With Adrenal Incidentalomas nanUNKNOWN
11C-Acetate PET/CT Non-FDG-Avid Tumors nanUNKNOWN
Mechanisms of Glucose Lowering Effect of Colesevelam HCl nanCOMPLETED
The Safety and Efficacy Study of RiaGev in Healthy Adults nanUNKNOWN
Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic Urolithiasis nanENROLLING_BY_INVITATION
Genetic Analysis of Human Hypertensive End Stage Renal Disease (H-ESRD) nanCOMPLETED
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH nanCOMPLETED
Effect of Genetic Differences on Levels of Water Disinfection Byproducts in Blood After Showering nanCOMPLETED
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome nanCOMPLETED
IVF Outcome in Polycystic Ovary Syndrome Patients nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a GRHPR binder may also engage these)

ProteinNameSimilarity
Q91Z53 — 1.000 Q91Z53 →
Q1R543 — 0.990 Q1R543 →
B5YVK6 — 0.990 B5YVK6 →
B7M3H6 — 0.990 B7M3H6 →
A7ZTA0 — 0.990 A7ZTA0 →
B7LTG7 — 0.990 B7LTG7 →
P58220 — 0.989 P58220 →
A8ARD9 — 0.989 A8ARD9 →
B1IZP1 — 0.989 B1IZP1 →
B7N1K7 — 0.989 B7N1K7 →
Q83PR3 — 0.989 Q83PR3 →
B1LJB3 — 0.989 B1LJB3 →
Q8FCF1 — 0.988 Q8FCF1 →
C4ZXE2 — 0.988 C4ZXE2 →
B7ULB4 — 0.988 B7ULB4 →
B2U573 — 0.988 B2U573 →
B2VCD1 — 0.988 B2VCD1 →
B7NP49 — 0.988 B7NP49 →
A8G7S7 — 0.988 A8G7S7 →
B7NEK6 — 0.988 B7NEK6 →
B1X8G8 — 0.988 B1X8G8 →
B4SWJ5 — 0.988 B4SWJ5 →
Q328L4 — 0.987 Q328L4 →
Q0TBP9 — 0.987 Q0TBP9 →
A4W577 — 0.987 A4W577 →
Q0SZE5 — 0.987 Q0SZE5 →
C0Q1A7 — 0.987 C0Q1A7 →
Q3YVT5 — 0.987 Q3YVT5 →
A7FPA2 — 0.987 A7FPA2 →
B5EX58 — 0.987 B5EX58 →