Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514165 | 0.86 | ESR1 (0.40) | ESR1ESR2BRD4HSP90AA1NPC1 | |
| SCHEMBL5506253 | 0.84 | ESR1 (0.39) | ESR1ESR2BRD4HSP90AA1 | |
| SCHEMBL5511899 | 0.84 | ESR1 (0.39) | ESR1ESR2BRD4HSP90AA1 | |
| SCHEMBL6988890 | 0.77 | BRD4 (0.53) | ESR1ESR2BRD4 | |
| SCHEMBL1759343 | 0.75 | MAPT (0.54) | ESR1ESR2NQO1NPC1RAB9A | |
| SCHEMBL1101176 | 0.75 | ESR1 (0.45) | ESR1ESR2HSP90AA1ALOX15NPC1 | |
| SCHEMBL5509963 | 0.74 | AHR (0.44) | ESR1ESR2HSP90AA1 | |
| SCHEMBL5511697 | 0.74 | ESR1 (0.41) | ESR1ESR2HSP90AA1 | |
| SCHEMBL12589377 | 0.71 | GRM4 (0.36) | ESR1ESR2BRD4ACHE | |
| SCHEMBL2137945 | 0.70 | ESR1 (0.61) | ESR1ESR2HSP90AA1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242495-A | COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | disclosed |