SCHEMBL2137945

SCHEMBL2137945

Oc1ccc2c(O)noc2c1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 19/20 0.61
▸ ESR2 Q92731 19/20 0.61
▸ HSP90AA1 P07900 3/20 0.61
▸ KDM4E B2RXH2 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5508112 0.83 ESR1 (0.63) ESR1ESR2HSP90AA1KDM4EALDH1A1
SCHEMBL30765144 0.79 ESR1 (0.58) ESR1ESR2HSP90AA1KDM4EALDH1A1
SCHEMBL745847 0.79 ESR1 (0.62) ESR1ESR2HSP90AA1KDM4EALDH1A1
SCHEMBL16360885 0.79 ESR1 (0.58) ESR1ESR2HSP90AA1KDM4EALDH1A1
SCHEMBL1836503 0.79 ALDH1A1 (0.49) ESR1ESR2HSP90AA1ALDH1A1MAPT
SCHEMBL8290795 0.79 ESR1 (0.41) ESR1ESR2HSP90AA1
SCHEMBL5512412 0.79 ESR1 (0.42) ESR1ESR2HSP90AA1KDM4EALDH1A1
SCHEMBL5514251 0.79 ACHE (0.41) ESR1ESR2HSP90AA1
SCHEMBL1101176 0.79 ESR1 (0.45) ESR1ESR2HSP90AA1MAPTALOX15
SCHEMBL3932748 0.76 ESR1 (1.00) ESR1ESR2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313704-A1 ALGICIDAL ORGANISMS PRO FARM GROUP, INC. 2025-10-09 — — US disclosed
US-20250287954-A1 METHOD AND COMPOSITION OF SYNERGISTIC INSECTICIDAL MIXTURES PRO FARM GROUP, INC. 2025-09-18 — — US disclosed
EP-4514135-A1 METHOD AND COMPOSITION OF SYNERGISTIC INSECTICIDAL MIXTURES Pro Farm Group, Inc. (US) 2025-03-05 — — EP disclosed
CN-119173143-A Methods and compositions for synergistic insecticidal mixtures 专业农场集团有限公司 2024-12-20 — — CN disclosed
WO-2023212708-A9 METHOD AND COMPOSITION OF SYNERGISTIC INSECTICIDAL MIXTURES PRO FARM GROUP, INC. (US) 2024-02-22 — — WO disclosed
EP-3537878-B1 ALGICIDAL ORGANISMS PRO FARM GROUP INC (US) 2023-11-22 — — EP disclosed
WO-2023212708-A1 METHOD AND COMPOSITION OF SYNERGISTIC INSECTICIDAL MIXTURES PRO FARM GROUP, INC. (US) 2023-11-02 — — WO disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20210282405-A1 ALGICIDAL ORGANISMS MARRONE BIO INNOVATIONS, INC. (US) 2021-09-16 — — US disclosed
US-20210274791-A1 COMPOSITIONS AND METHODS TO TREAT CITRUS GREENING DISEASE MARRONE BIO INNOVATIONS, INC. (US) 2021-09-09 — — US disclosed
WO-2013130680-A1 CONTROL OF PHYTOPATHOGENIC MICROORGANISMS WITH PSEUDOMONAS SP. AND SUBSTANCES AND COMPOSITIONS DERIVED THEREFROM MARRONE BIO INNOVATIONS, INC. (US) 2013-09-06 — — WO disclosed
US-20120100236-A1 CHROMOBACTERIUM BIOACTIVE COMPOSITIONS AND METABOLITES MARRONE BIO INNOVATIONS, INC. (US) 2012-04-26 — — US disclosed
US-20100028469-A1 Extracts of Cranberry and Methods of Using Thereof HERBALSCIENCE GROUP, LLC (US) 2010-02-04 — — US disclosed
US-7166725-B2 Benzo[d]isoxazol-3-ol DAAO inhibitors SEPRACOR INC. (US) 2007-01-23 — — US disclosed
US-7166725-B2 Benzo[d]isoxazol-3-ol DAAO inhibitors SEPRACOR INC. (US) 2007-01-23 — — US disclosed
US-7166725-B2 Benzo[d]isoxazol-3-ol DAAO inhibitors SEPRACOR INC. (US) 2007-01-23 — — US disclosed
EP-1711478-A2 BENZO [D]ISOXAZOL-3-OL DAAO INHIBITORS Sepracor Inc. (US) 2006-10-18 — — EP disclosed
WO-2005066143-A2 BENZO[D]ISOXAZOL-3-OL DAAO INHIBITORS SEPRACOR INC. (US) 2005-07-21 — — WO disclosed
WO-2005066143-A2 BENZO[D]ISOXAZOL-3-OL DAAO INHIBITORS SEPRACOR INC. (US) 2005-07-21 — — WO disclosed
US-20050143434-A1 Benzo[d]isoxazol-3-ol DAAO inhibitors SEPRACOR INC. (US) 2005-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143434-A1 Benzo[d]isoxazol-3-ol DAAO inhibitors DDO, DAO, CACNA1S ESR1 2250/4885ESR2 3052/4885HSP90AA1 3107/4885
US-20250287954-A1 METHOD AND COMPOSITION OF SYNERGISTIC INSECTICIDAL MIXTURES CRYAB, CRYAA, STXBP1 ESR1 4294/4885ESR2 3116/4885HSP90AA1 510/4885
US-20120100236-A1 CHROMOBACTERIUM BIOACTIVE COMPOSITIONS AND METABOLITES CBX3, CBX7, CBX6 ESR1 2916/4885ESR2 3157/4885HSP90AA1 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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