Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | PRLHR | P49683 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445096 | 0.78 | CYP3A4 (0.45) | CYP2C9MAPTHDAC2HDAC8HDAC6 | |
| SCHEMBL11445186 | 0.77 | CYP3A4 (0.43) | ABCG2ABCB1CYP2C9PTGDR2MAPT | |
| SCHEMBL9529005 | 0.75 | ABCG2 (0.45) | ABCG2ABCB1P2RX4CYP2C9PTGDR2 | |
| SCHEMBL11445326 | 0.74 | TSHR (0.41) | ABCG2ABCB1CYP2C9MAPTHDAC2 | |
| Hydrochloric Acid SCHEMBL10491435 | 0.74 | ABCG2 (0.45) | ABCG2ABCB1P2RX4CYP2C9PTGDR2 | |
| SCHEMBL11445911 | 0.74 | CYP3A4 (0.42) | CYP2C9MAPTHDAC2HDAC8HDAC6 | |
| SCHEMBL11471795 | 0.71 | CYP3A4 (0.46) | CYP2C9MAPTHDAC2HDAC8HDAC6 | |
| SCHEMBL11445097 | 0.70 | CYP3A4 (0.39) | CYP2C9MAPTHDAC2HDAC8HDAC6 | |
| SCHEMBL11472172 | 0.70 | HDAC2 (0.46) | CYP2C9MAPTHDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL11485438 | 0.70 | CYP3A4 (0.45) | CYP2C9MAPTHDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |