Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445186 | 0.93 | CYP3A4 (0.43) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11472270 | 0.90 | HDAC2 (0.44) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11472105 | 0.87 | CYP3A4 (0.48) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11468999 | 0.86 | HDAC2 (0.45) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11472043 | 0.85 | CYP3A4 (0.47) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11477225 | 0.85 | PER2 (0.47) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11469508 | 0.84 | CYP3A4 (0.44) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11481565 | 0.84 | CYP3A4 (0.43) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11477027 | 0.83 | CYP3A4 (0.45) | HDAC2HDAC8HDAC6CYP3A4TSHR | |
| SCHEMBL11445326 | 0.83 | TSHR (0.41) | HDAC2HDAC8HDAC6CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |