Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 known ✓ | P04629 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433669 | 0.78 | NPC1 (0.40) | NPC1RAB9AL3MBTL1TRPV1CYP19A1 | |
| SCHEMBL11439269 | 0.71 | CYP3A4 (0.51) | NPC1RAB9AL3MBTL1CYP19A1CYP3A4 | |
| SCHEMBL11434368 | 0.71 | CYP19A1 (0.39) | NPC1RAB9AL3MBTL1CYP19A1CYP3A4 | |
| SCHEMBL11441820 | 0.68 | NPC1 (0.43) | NPC1RAB9AL3MBTL1CYP19A1SMN1; SMN2 | |
| SCHEMBL11433779 | 0.68 | NPC1 (0.47) | NPC1RAB9AL3MBTL1CYP19A1CYP3A4 | |
| SCHEMBL11442557 | 0.66 | NPC1 (0.50) | NPC1RAB9AL3MBTL1TRPV1CYP19A1 | |
| SCHEMBL14882398 | 0.64 | TSHR (0.44) | TRPV1MMP13SMN1; SMN2HTTTP53 | |
| SCHEMBL11439287 | 0.63 | NPC1 (0.47) | NPC1RAB9AL3MBTL1CYP19A1CYP3A4 | |
| Bromide SCHEMBL11433766 | 0.63 | CNR1 (0.43) | NPC1CYP19A1CYP3A4CYP3A5SMN1; SMN2 | |
| SCHEMBL14875134 | 0.63 | TSHR (0.42) | TRPV1MMP13SMN1; SMN2HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |