Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623794 | 0.90 | MAPK1 (0.60) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10625894 | 0.89 | MAPK1 (0.62) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11464258 | 0.84 | ALDH1A1 (0.61) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10620885 | 0.84 | MAPT (0.53) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10625637 | 0.82 | MAPK1 (0.57) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10621418 | 0.77 | ROCK1 (0.52) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL10620858 | 0.76 | EED (0.47) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10621375 | 0.76 | EED (0.52) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10620782 | 0.76 | MAPT (0.62) | MAPK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10620800 | 0.76 | MAPT (0.64) | MAPK1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4186199-A | Indolo-,1,2-dihydroindolo-, and 1,2,6,7-tetrahydroindolo [1,7-ab][1,5] benzodiazepines | AMERICAN HOECHST CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |