Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 8/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1154135 | 1.00 | AKR1B1 (0.42) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL6860570 | 1.00 | AKR1B1 (0.42) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL6865097 | 0.97 | AKR1B1 (0.40) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL28200026 | 0.97 | AKR1B1 (0.40) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL17491791 | 0.97 | AKR1B1 (0.40) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL948487 | 0.97 | CES1 (0.44) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL7942510 | 0.97 | AKR1B1 (0.40) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL28521369 | 0.97 | CES1 (0.44) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL28334359 | 0.97 | AKR1B1 (0.40) | AKR1B1PPARDGPR84PPARGPPARA | |
| Acetic Acid SCHEMBL9796471 | 0.95 | AKR1B1 (0.39) | AKR1B1PPARDGPR84PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2951 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119592294-B | Quick-curing bi-component condensation dealcoholized silicone adhesive and preparation method thereof | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037137-A | Organosilicon modified polyurethane acrylic ester, and preparation method and application thereof | 合肥中聚和成光电材料股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4638634-A1 | DUALLY CURABLE ADHESIVE COMPOSITION | Henkel AG & Co. KGaA (DE) | 2025-10-29 | — | — | EP | claimed |
| US-20250313735-A1 | Dually Curable Adhesive Composition | HENKEL AG & CO. KGAA (DE) | 2025-10-09 | — | — | US | claimed |
| CN-120118661-A | Thermal interface material, preparation method and application | 深圳先进电子材料国际创新研究院 | 2025-06-10 | — | — | CN | claimed |
| CN-119841605-A | High-strength heat-preservation gangue foam concrete, and preparation method and application thereof | 山东交通学院 | 2025-04-18 | — | — | CN | claimed |
| CN-119592294-A | Quick-curing bi-component condensation dealcoholized silicone adhesive and preparation method thereof | 万华化学集团股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119490814-A | Bi-component condensation deacidification type silicone adhesive capable of being rapidly and deeply cured and preparation method thereof | 万华化学集团股份有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-119039692-B | B1 flame-retardant grade silane crosslinked low-smoke halogen-free flame-retardant polyolefin insulating material and preparation method thereof | 凯波特材(安徽)有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118530690-B | High-performance sealant and preparation method and application thereof | 长春中科应化特种材料股份有限公司 | 2025-01-21 | — | — | CN | claimed |
| US-5144058-A | Colorless grained alpha-form crystals of tetrakis [3-(3,5-di-t-butyl-4-hydroxyphenyl)propionyloxymethyl]methane and process for its manufacture | INTERNATIONAL CHEMICAL CONSULTANT, LTD. (JP) | 1992-09-01 | — | — | US | claimed |
| EP-0448775-A2 | Colorless grained alpha-form crystals of tetrakis [3-(3,5-Di-T-butyl-4-hydroxyphenyl)propionyloxymethyl]methane and process for its manufacture | INTERNATIONAL CHEMICAL CONSULTANT, LTD. (JP) | 1991-10-02 | — | — | EP | claimed |
| US-4987180-A | SOFTNESS, ELASTIC RESILIENCE, WINDPROOFING, WASHFASTNESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | claimed |
| CN-1009392-B | Composite lead intensifying screen for industrial X-ray flaw detection | UNIV TIANJIN (CN) | 1990-08-29 | — | — | CN | claimed |
| EP-0338417-A2 | Haze-free infrared-reflecting coated glass | PPG INDUSTRIES, INC. (US) | 1989-10-25 | — | — | EP | claimed |
| CN-1034271-A | Sensitivity enhanced screen made of compound lead for industrial X-ray fanlt detection | UNIV TIANJIN (CN) | 1989-07-26 | — | — | CN | claimed |
| EP-0255252-A2 | Process for cosynthesis of ethylene glycol and dimethyl carbonate | TEXACO DEVELOPMENT CORPORATION (US) | 1988-02-03 | — | — | EP | claimed |
| US-4661609-A | TRANSESTERIFICATION OF METHANOL AND ETHYLENE CARBONATE WITH ZIRCONIUM, TITANIUM OR TIN CONTAINING CATALYST | TEXACO INC. (US) | 1987-04-28 | — | — | US | claimed |
| US-4530975-A | Reacting a polyisocyanate compound and polycarboxylic acid | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1985-07-23 | — | — | US | claimed |
| US-4330657-A | Process for the production of storage-stable urethane acryls | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | claimed |