Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 8/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28521369 | 1.00 | CES1 (0.44) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL114460 | 0.97 | AKR1B1 (0.42) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL6860570 | 0.97 | AKR1B1 (0.42) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL1154135 | 0.97 | AKR1B1 (0.42) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL28200026 | 0.95 | AKR1B1 (0.40) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL28334359 | 0.95 | AKR1B1 (0.40) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL6865097 | 0.95 | AKR1B1 (0.40) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL17491791 | 0.95 | AKR1B1 (0.40) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL7942510 | 0.95 | AKR1B1 (0.40) | CES1AKR1B1PPARDGPR84PPARG | |
| Acetic Acid SCHEMBL9796471 | 0.92 | AKR1B1 (0.39) | CES1AKR1B1PPARDGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993727-B2 | Antifouling coating film and method of manufacturing same, water contacting structure with antifouling coating film, and antifouling tape and method of manufacturing same | CHUGOKU MARINE PAINTS, LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| CN-117999324-A | Antifouling coating composition | 中国涂料株式会社 | 2024-05-07 | — | — | CN | disclosed |
| EP-3467058-B1 | ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM, LAMINATED ANTIFOULING COATING FILM, BASE MEMBER PROVIDED WITH ANTIFOULING COATING FILM AND METHOD FOR PRODUCING SAME, AND ANTIFOULING METHOD | CHUGOKU MARINE PAINTS (JP) | 2024-02-21 | — | — | EP | disclosed |
| WO-2023204213-A1 | ANTIFOULING COATING COMPOSITION | 中国塗料株式会社 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023054487-A1 | ANTIFOULING COATING COMPOSITION | 中国塗料株式会社 | 2023-04-06 | — | — | WO | disclosed |
| US-11555134-B2 | Acrylic polysiloxane resin coating compositions and uses thereof | CHUGOKU MARINE PAINTS, LTD. (JP) | 2023-01-17 | — | — | US | disclosed |
| EP-3564331-B1 | ANTI-FOULING PAINT COMPOSITION, ANTI-FOULING PAINT FILM, BASE MATERIAL HAVING ANTI-FOULING PAINT FILM ATTACHED THERETO AND METHOD FOR PRODUCING SAME, AND FOULING PREVENTION METHOD | CHUGOKU MARINE PAINTS (JP) | 2021-11-17 | — | — | EP | disclosed |
| EP-3885134-A1 | ANTIFOULING COATING FILM WITH COVER FILM, METHOD FOR PRODUCING SAME, ANTIFOULING TAPE, AND METHOD FOR PRODUCING STRUCTURE WHICH HAS ANTIFOULING COATING FILM AND IS IN CONTACT WITH WATER | Chugoku Marine Paints, Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
| CN-110114426-B | Antifouling coating composition, antifouling coating film, substrate with antifouling coating film, method for producing substrate with antifouling coating film, and antifouling method | 中国涂料株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-111373005-B | Acrylic polysiloxane resin-based coating composition and use thereof | 中国涂料株式会社 | 2021-07-09 | — | — | CN | disclosed |
| US-20070049768-A1 | COMPOSITION OF VINYL ETHER GROUP CONTAINING (METH) ACRYLIC ACID ESTER AND PRODUCTION METHOD THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| WO-2006060272-A2 | PROCESS AND COMPOSITION FOR COATING PROPAGATION MATERIAL | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-08 | — | — | WO | disclosed |
| US-6872493-B2 | Nonaqueous electrolytic solution and nonaqueous secondary battery | DENSO CORPORATION (JP) | 2005-03-29 | — | — | US | disclosed |
| EP-1505090-A1 | REACTIVE DILUENT COMPOSITION AND CURABLE RESIN COMPOSITION | Nippon Shokubai Co., Ltd. (JP) | 2005-02-09 | — | — | EP | disclosed |
| US-6767980-B2 | ACTIVATED ENERGY RAY-CURABLE INK COMPOSITION FOR INK-JET PRINTING; VINYL ETHER GROUP-CONTAINING (METH)ACRYLIC ESTER | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-07-27 | — | — | US | disclosed |
| US-20030199655-A1 | Reactive diluent and curable resin composition | NIPPON SHOKUBAI CO., LTD. | 2003-10-23 | — | — | US | disclosed |
| US-20020143120-A1 | Composition of vinyl ether group-containing (meth) acrylic acid ester and production method thereof | NIPPON SHOKUBAI CO., LTD. | 2002-10-03 | — | — | US | disclosed |
| US-20020076619-A1 | Nonaqueous electrolytic solution and nonaqueous secondary battery | ADEKA CORPORATION (JP) | 2002-06-20 | — | — | US | disclosed |
| EP-1201641-A2 | Composition of vinyl ether group containing (meth)acrylic acid ester and production method thereof | Nippon Shokubai Co., Ltd. (JP) | 2002-05-02 | — | — | EP | disclosed |
| EP-1202373-A2 | Nonaqueous electrolytic solution and nonaqueous secondary battery | DENSO CORPORATION (JP) | 2002-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993727-B2 | Antifouling coating film and method of manufacturing same, water contacting structure with antifouling coating film, and antifouling tape and method of manufacturing same | ZFP3, RCSD1, NOTUM | ESR1 4270/4885CES1 1777/4885AKR1B1 2491/4885 |
| US-20070049768-A1 | COMPOSITION OF VINYL ETHER GROUP CONTAINING (METH) ACRYLIC ACID ESTER AND PRODUCTION METHOD THEREOF | MMAB, ME1, PRMT1 | ESR1 1389/4885CES1 148/4885AKR1B1 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.