Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140315 | 0.67 | PTGS1 (0.54) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL2597029 | 0.67 | PTGS1 (0.54) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL4274818 | 0.64 | PTGS1 (0.47) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL11446070 | 0.63 | CYP3A4 (0.34) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL11753142 | 0.62 | MEN1 (0.43) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL4278705 | 0.62 | PTGS1 (0.48) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL8101375 | 0.61 | PTGS1 (0.38) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL4274823 | 0.61 | PTGS1 (0.47) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL8376063 | 0.61 | MEN1 (0.44) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL4482722 | 0.61 | PTGS1 (0.47) | CYP3A4PTGS1PTGS2CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208426-A | Pyranochromone derivatives and therapeutic composition comprising same for treatment of allergic diseases | EISAI CO., LTD. (JP) | 1980-06-17 | — | — | US | disclosed |