Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | TTPA | P49638 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753142 | 0.84 | MEN1 (0.43) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7331108 | 0.76 | MEN1 (0.55) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL13592375 | 0.76 | MEN1 (0.48) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL5268436 | 0.74 | MEN1 (0.56) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10535364 | 0.72 | MEN1 (0.54) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8618091 | 0.72 | MEN1 (0.54) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL7331962 | 0.71 | MEN1 (0.53) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8601773 | 0.71 | MEN1 (0.53) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8599804 | 0.71 | MEN1 (0.53) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8599834 | 0.71 | MEN1 (0.47) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7097380-A | — | — | None | — | — | JP | disclosed |
| EP-0645383-B1 | Process for producing chromanes | KURARAY CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5495026-A | Process for producing chroman | KURARAY COMPANY LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| JP-H0797380-A | PRODUCTION OF CHROMAN COMPOUND | KURARAY CO LTD | 1995-04-11 | — | — | JP | disclosed |
| EP-0645383-A1 | Process for producing chroman | KURARAY CO., LTD. (JP) | 1995-03-29 | — | — | EP | disclosed |