Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | MME | P08473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446870 | 1.00 | FOLH1 (0.57) | FOLH1ACEMMEKDM4EUSP2 | |
| SCHEMBL11454560 | 1.00 | FOLH1 (0.57) | FOLH1ACEMMEKDM4EUSP2 | |
| SCHEMBL11792982 | 0.88 | SLC7A5 (0.68) | FOLH1ACEMMEKDM4EUSP2 | |
| SCHEMBL11854644 | 0.88 | LCK (0.60) | KDM4EUSP2EGFRLCKFYN | |
| SCHEMBL13925361 | 0.87 | LCK (0.58) | FOLH1ACEMMEKDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL11454672 | 0.87 | SLC7A5 (0.66) | FOLH1ACEMMEKDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL4117118 | 0.86 | LCK (0.57) | FOLH1ACEMMEKDM4EUSP2 | |
| SCHEMBL11856676 | 0.86 | LCK (0.49) | FOLH1ACEMMEKDM4EUSP2 | |
| SCHEMBL11056714 | 0.86 | FOLH1 (0.69) | FOLH1ACEMMESLC7A5CPA1 | |
| SCHEMBL2474675 | 0.86 | FOLH1 (0.69) | FOLH1ACEMMESLC7A5CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241082-A | 3,4-DIHYDROXYPHENYLALANINE OR DERIVATIVE THEREOF AS A DECARBOXYLASE INHIBITOR USED IN CONJUNCTION WITH AN AMINO ACID | SANKYO COMPANY LIMITED (JP) | 1980-12-23 | — | — | US | claimed |