Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.60 |
| ▸ | NPY4R | P50391 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 6/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856676 | 0.91 | LCK (0.49) | LCKNPY4RNPY1RIL1RNERAP2 | |
| SCHEMBL11857999 | 0.91 | LCK (0.54) | LCKNPY4RNPY1RIL1RNERAP2 | |
| SCHEMBL11849660 | 0.90 | LCK (0.65) | LCKERAP2ERAP1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL11684930 | 0.89 | LCK (0.64) | LCKERAP2ERAP1HSD17B10KDM4E | |
| SCHEMBL11454560 | 0.88 | FOLH1 (0.57) | LCKNPY4RNPY1RHSD17B10KDM4E | |
| SCHEMBL11446869 | 0.88 | FOLH1 (0.57) | LCKNPY4RNPY1RHSD17B10KDM4E | |
| SCHEMBL11446870 | 0.88 | FOLH1 (0.57) | LCKNPY4RNPY1RHSD17B10KDM4E | |
| SCHEMBL11859692 | 0.87 | ERAP2 (0.49) | LCKIL1RNERAP2ERAP1 | |
| SCHEMBL27431221 | 0.86 | ERAP2 (0.62) | NPY4RNPY1RIL1RNERAP2ERAP1 | |
| SCHEMBL11859518 | 0.85 | LCK (0.59) | LCKERAP2HSD17B10KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |