Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.56 |
| ▸ | HRH2 | P25021 | 7/20 | 0.56 |
| ▸ | HRH1 | P35367 | 7/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448117 | 0.97 | HRH3 (0.56) | HRH3HRH2HRH1SLC6A4CHRM3 | |
| SCHEMBL11466251 | 0.87 | HCRTR1 (0.56) | HRH1SLC6A4 | |
| SCHEMBL14577990 | 0.86 | LTA4H (0.51) | HRH3 | |
| SCHEMBL11459353 | 0.85 | CHRNB4 (0.55) | HRH2CHRM3 | |
| SCHEMBL11455837 | 0.85 | HRH3 (0.52) | HRH3 | |
| SCHEMBL11448034 | 0.85 | KDM4E (0.51) | HRH3 | |
| SCHEMBL11457025 | 0.85 | SLC2A1 (0.53) | HRH3 | |
| SCHEMBL11448915 | 0.84 | SLC2A1 (0.58) | — | |
| SCHEMBL11466424 | 0.84 | CHRNB4 (0.55) | HRH1SLC6A4CHRM3 | |
| SCHEMBL11447668 | 0.83 | ESRRG (0.59) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |