Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448605 | 1.00 | APP (0.54) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL29928086 | 0.91 | APP (0.63) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL6807684 | 0.91 | APP (0.63) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL14373940 | 0.88 | RAB9A (0.67) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL24332467 | 0.86 | APP (0.58) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL24332276 | 0.86 | APP (0.58) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL24332167 | 0.86 | APP (0.58) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL24332465 | 0.86 | APP (0.58) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL24331811 | 0.84 | APP (0.57) | APPRAB9ANPC1KDM4EGLA | |
| SCHEMBL24332090 | 0.84 | APP (0.57) | APPRAB9ANPC1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220760-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-02 | — | — | US | disclosed |