SCHEMBL11448641

SCHEMBL11448641

C=CC(C)C#CC(C)CCC=C(C)C

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.41
SRC P12931 1/20 0.31
SQLE Q14534 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5043554 0.76 ALOX15 (0.47) ALOX15TSHRALDH1A1SRC
SCHEMBL11448639 0.74 TSHR (0.42) ALOX15TSHRALDH1A1SQLE
SCHEMBL9515041 0.74 ALOX15 (0.48) ALOX15TSHRALDH1A1SRCSQLE
Beta-Citronellene SCHEMBL2456981 0.71 ALOX15 (0.50) ALOX15TSHRALDH1A1SRC
Beta-Citronellene SCHEMBL21872 0.71 ALOX15 (0.50) ALOX15TSHRALDH1A1SRC
Beta-Citronellene SCHEMBL7808244 0.71 ALOX15 (0.50) ALOX15TSHRALDH1A1SRC
SCHEMBL7789930 0.70 ALOX15 (0.48) ALOX15TSHRALDH1A1SRC
SCHEMBL14331466 0.70 ALOX15 (0.48) ALOX15TSHRALDH1A1SRC
SCHEMBL14323435 0.70 ALOX15 (0.48) ALOX15TSHRALDH1A1SRC
SCHEMBL11455401 0.69 ALOX15 (0.47) ALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4226892-A Flavoring with cycloaliphatic unsaturated ketones FIRMENICH SA (CH) 1980-10-07 US disclosed
US-4187863-A Cycloaliphatic unsaturated ketones as odor and taste modifying agents in tobacco products FIRMENICH SA (CH) 1980-02-12 US disclosed
US-3975310-A PERFUME FIRMENICH S.A. (CH) 1976-08-17 US disclosed
US-3931326-A FLAVOR, TASTE, ODOR, PERFUMES FIRMENICH SA (CH) 1976-01-06 US disclosed