Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956697 | 0.88 | PKM (0.71) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11560938 | 0.83 | PKM (0.65) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL16566509 | 0.83 | PKM (0.65) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL22974794 | 0.79 | PKM (0.59) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11449325 | 0.78 | PKM (0.53) | PKMKCNA3ALDH1A1TAAR1RECQL | |
| SCHEMBL1309388 | 0.77 | PKM (0.67) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL22773975 | 0.77 | KCNA3 (0.64) | PKMKCNA3CYP2C9CYP2C19HDAC3 | |
| SCHEMBL427191 | 0.77 | PKM (0.67) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL10936851 | 0.77 | PKM (0.67) | PKMKCNA3CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11450817 | 0.76 | PKM (0.51) | PKMTAAR1PARP10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231781-A | Halophenoxy-alkoxy phosphonates and thiophosphonates | GAF CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |