Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL2177860 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL10493311 | 0.91 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1GABBR2GABBR1 | |
| Propylene Glycol SCHEMBL7622439 | 0.87 | — | — | |
| Isopropyl Alcohol SCHEMBL27792282 | 0.86 | — | — | |
| Isopropyl Alcohol SCHEMBL5806473 | 0.86 | ALDH1A1 (0.61) | TSHRALDH1A1TDP1TRPV1TRPA1 | |
| Isopropyl Alcohol SCHEMBL1289871 | 0.86 | ALDH1A1 (0.61) | TSHRALDH1A1TDP1TRPV1TRPA1 | |
| SCHEMBL9387 | 0.86 | — | — | |
| Hydroxyamine SCHEMBL27483582 | 0.86 | — | — | |
| SCHEMBL362926 | 0.86 | — | — | |
| SCHEMBL5036885 | 0.86 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1TRPV1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233284-A | GENESTIC ACID, SALT OR ESTER THEREOF IN COMBINATION WITH A PERTECHNETATE REDUCING AGENT BECOMES LOCALIZED IN SPECIFIC BODY ORGANS OR BONES | THE PROCTER & GAMBLE COMPANY (US) | 1980-11-11 | — | — | US | disclosed |