SCHEMBL114513

SCHEMBL114513

CCCCCC[SiH2]C(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
THRB P10828 1/20 0.38
DNM1 Q05193 7/20 0.33
PRKD3 O94806 3/20 0.32
PRKCG P05129 3/20 0.32
PRKCB P05771 3/20 0.32
PRKCA P17252 3/20 0.32
PRKCH P24723 3/20 0.32
PRKCI P41743 3/20 0.32
PRKCE Q02156 3/20 0.32
PRKCQ Q04759 3/20 0.32
PRKCZ Q05513 3/20 0.32
PRKCD Q05655 3/20 0.32
PRKD1 Q15139 3/20 0.32
ZDHHC7 Q9NXF8 1/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
LPAR6 P43657 1/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR4 Q99677 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114287 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL17750065 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL2389523 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL27856729 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL114101 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL12805406 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL27857855 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL17750050 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL28308439 1.00 TSHR (0.38) TSHRTHRBDNM1PRKD3PRKCG
SCHEMBL3655928 0.90 CA1 (0.31) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3187558-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MAT INC (US) 2021-03-24 EP claimed
EP-2691464-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE MOMENTIVE PERFORMANCE MAT INC (US) 2019-01-09 EP claimed
EP-3187558-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS Momentive Performance Materials Inc. (US) 2017-07-05 EP claimed
EP-2424949-B1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MAT INC (US) 2017-03-01 EP claimed
CN-104130415-A Organosilicon quaternary ammonium salt containing alkyl group and glycosylamide group, and preparation method thereof UNIV BEIJING TECH & BUSINESS 2014-11-05 CN claimed
US-20140323650-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. 2014-10-30 US claimed
CN-102459487-B Moisture-curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-29 CN claimed
US-8809479-B2 Moisture curable silylated polymer compositions containing reactive modifiers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-08-19 US claimed
CN-102492146-B Method for preparing polysiloxane containing alkyl and glucosamide UNIV BEIJING TECH & BUSINESS 2013-06-12 CN claimed
CN-102492146-A Method for preparing polysiloxane containing alkyl and glucosamide UNIV BEIJING TECH & BUSINESS 2012-06-13 CN claimed
EP-2424949-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS Momentive Performance Materials Inc. (US) 2012-03-07 EP claimed
US-20100317796-A1 Moisture Curable Silylated Polymer Compositions Containing Reactive Modifiers MOMENTIVE PERFORMANCE MATERIALS INC. 2010-12-16 US claimed
WO-2010126937-A1 MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-04 WO claimed
US-12559632-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials UNIVERSITY OF HOUSTON SYSTEM (US) 2026-02-24 US disclosed
US-12312534-B2 Treating fluid comprising hydrocarbons, water, and polymer CHEVRON U.S.A. INC. (US) 2025-05-27 US disclosed
US-12215276-B2 Ph control in fluid treatment CHEVRON U.S.A. INC. (US) 2025-02-04 US disclosed
US-20060009650-A1 3-iodopropylmethyldiisopropoxysilane and imaging members including the same XEROX CORPORATION 2006-01-12 US disclosed
US-6852460-B2 Toner and image forming method using the same KYOCERA CORPORATION (JP) 2005-02-08 US disclosed
US-20030186151-A1 Toner and image forming method using the same KYOCERA CORPORATION 2003-10-02 US disclosed
CN-1383037-A Organic toner and picture forming method using same KYOCERA CORP (JP) 2002-12-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559632-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials GMDS, MGAM, STS TSHR 2419/4885THRB 2832/4885DNM1 4053/4885
US-20060009650-A1 3-iodopropylmethyldiisopropoxysilane and imaging members including the same NR2E3, ALDH1A2, PDE6C TSHR 137/4885THRB 737/4885DNM1 3095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.