SCHEMBL11452467

SCHEMBL11452467

O=C(O)COc1ccc(/C=C/C(=O)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.70
MEN1 O00255 2/20 0.70
NPC1 O15118 2/20 0.67
RAB9A P51151 2/20 0.67
POLB P06746 1/20 0.67
BLM P54132 1/20 0.67
GPR35 Q9HC97 1/20 0.67
XDH P47989 1/20 0.67
MAOB P27338 8/20 0.59
MAOA P21397 1/20 0.59
MAPT P10636 1/20 0.59
ABCG2 Q9UNQ0 3/20 0.58
CYSLTR2 Q9NS75 1/20 0.58
F3 P13726 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinfenoac SCHEMBL10543583 1.00 KMT2A (0.70) KMT2AMEN1NPC1RAB9APOLB
Cinfenoac SCHEMBL25209635 1.00 KMT2A (0.70) KMT2AMEN1NPC1RAB9APOLB
Cinfenoac SCHEMBL1516598 1.00 KMT2A (0.70) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL11452470 1.00 KMT2A (0.70) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL30382929 0.99 KMT2A (0.68) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL11451947 0.99 KMT2A (0.68) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL11451943 0.99 KMT2A (0.68) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL11459734 0.95 KMT2A (0.75) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL11459733 0.95 KMT2A (0.75) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL25199811 0.90 KMT2A (0.76) KMT2AMEN1NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-4190671-A ANTIINFLAMMATORY, ANTIALLERGENIC, ANTIULCER BIOREX LABORATORIES LIMITED (GB) 1980-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B KMT2A 2792/4885MEN1 3367/4885NPC1 1378/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885NPC1 1908/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885NPC1 1908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.