Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145434 | 0.81 | CA1 (0.39) | CA12CA1CA2CA14TSHR | |
| SCHEMBL1146109 | 0.70 | CA1 (0.33) | CA12CA1CA2CA14TSHR | |
| Sulfuric Acid SCHEMBL27095073 | 0.69 | TP53 (0.33) | TSHR | |
| Sulfamate SCHEMBL8822931 | 0.67 | CA1 (0.50) | CA12CA1CA2CA14TSHR | |
| SCHEMBL42537 | 0.66 | CA1 (0.38) | CA12CA1CA2CA14 | |
| SCHEMBL27482301 | 0.65 | — | — | |
| SCHEMBL1408715 | 0.65 | — | — | |
| SCHEMBL4330063 | 0.64 | TSHR (0.39) | TSHR | |
| SCHEMBL11045664 | 0.62 | TSHR (0.44) | TSHR | |
| SCHEMBL10629420 | 0.62 | TSHR (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7887824-B2 | such as N,N'-bis(2-hydroxyethyl)sulfamide; improved elasticity on stratum corneum | L'OREAL (FR) | 2011-02-15 | — | — | US | disclosed |
| EP-1669060-B9 | New sulfamide derivatives and their cosmetic use | OREAL (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1669060-B1 | New sulfamide derivatives and their cosmetic use | OREAL (FR) | 2008-05-07 | — | — | EP | disclosed |