Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CCR4 | P51679 | 1/20 | 0.56 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254898 | 0.95 | KMT2A (0.54) | KMT2AKDM4EARMAPK1CCR4 | |
| SCHEMBL19196708 | 0.90 | KMT2A (0.52) | KMT2AKDM4EARMAPK1CCR4 | |
| SCHEMBL11466274 | 0.87 | CYP19A1 (0.59) | KMT2AKDM4EARMAPK1SREBF2 | |
| SCHEMBL5254896 | 0.84 | KMT2A (0.45) | KMT2AKDM4EARMAPK1CCR4 | |
| SCHEMBL17348248 | 0.82 | NPC1 (0.56) | KMT2AKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2781370 | 0.81 | KDM4E (0.85) | KMT2AKDM4EARSREBF2RAB9A | |
| SCHEMBL23212840 | 0.80 | RAB9A (0.62) | KMT2AKDM4EARMAPK1RAB9A | |
| SCHEMBL23742623 | 0.80 | RAB9A (0.63) | KMT2AKDM4EARMAPK1SREBF2 | |
| SCHEMBL11213828 | 0.79 | SREBF2 (0.82) | KMT2AKDM4EARSREBF2RAB9A | |
| SCHEMBL11212983 | 0.79 | SREBF2 (0.82) | KMT2AKDM4EARSREBF2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197306-A | CONTROL OF INSECTS AND ACARIDS | UNIROYAL, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |