Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SQOR | Q9Y6N5 | 7/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920951 | 0.84 | MAPK8 (0.56) | MAPK8MAPK9RECQLSQORGSK3A | |
| SCHEMBL17163957 | 0.84 | RECQL (0.67) | MAPK8MAPK9RECQLSQORGSK3A | |
| SCHEMBL1145009 | 0.81 | MAPK8 (0.60) | MAPK8MAPK9PRKD3MAP4K4MAP4K2 | |
| SCHEMBL1145445 | 0.81 | MAPK8 (0.60) | MAPK8MAPK9GSK3BPRKD3MAP4K4 | |
| SCHEMBL1145819 | 0.80 | MAPK8 (0.48) | MAPK8MAPK9SQORPRKD3MAP4K4 | |
| SCHEMBL1145762 | 0.77 | MAPK8 (0.63) | MAPK8MAPK9PRKD3MAP4K4MAP4K2 | |
| SCHEMBL1145775 | 0.75 | MAPK8 (0.49) | MAPK8MAPK9ADORA1PRKD3MAP4K4 | |
| SCHEMBL1145344 | 0.75 | SMN1; SMN2 (0.56) | MAPK8MAPK9ADORA1ADORA2AKDM4E | |
| SCHEMBL1146078 | 0.75 | MAPK8 (0.45) | MAPK8MAPK9GSK3BPRKD3MAP4K4 | |
| SCHEMBL7893174 | 0.74 | KDM4E (0.48) | RECQLADORA1ADORA2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888374-B2 | Inhibitors of c-jun N-terminal kinases | ABBOTT LABORATORIES (US) | 2011-02-15 | — | — | US | disclosed |
| US-20090142554-A1 | Yellow Azo Dyes for Ink Jet Printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-06-04 | — | — | US | disclosed |
| US-20090142554-A1 | Yellow Azo Dyes for Ink Jet Printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-06-04 | — | — | US | disclosed |
| WO-2007045829-A2 | YELLOW AZO DYES FOR INK JET PRINTING | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2007-04-26 | — | — | WO | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | MAPKAPK3, MAP3K3, MAPK3 | MAPK8 30/4885MAPK9 49/4885RECQL 4594/4885 |
| US-20090142554-A1 | Yellow Azo Dyes for Ink Jet Printing | NR4A3, NR4A1, NR2E3 | MAPK8 1130/4885MAPK9 1695/4885RECQL 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.